Key result
Peritoneal dialysis linked to ~27% higher 7-day hospitalization risk versus hemodialysis.
Why the study?
Hospitalizations of chronic dialysis patients have not been previously studied at a national level in Canada, limiting understanding of associated risk factors and outcomes.
Does peritoneal dialysis compared to hemodialysis affect the risk of all-cause and infection-related hospitalizations in incident chronic dialysis patients?
Population
38,369 incident chronic dialysis patients in Canada excluding Manitoba and Quebec
Comparison
Peritoneal dialysis vs hemodialysis
Design
Retrospective cohort study using health care administrative databases
Follow-up
Up to 12 months postdialysis initiation
Authors
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Early hospitalization risk may be higher with peritoneal dialysis; should not change practice and leaves open causal effects beyond 7 days.
Cohort (n=38,369)
Yes
Does peritoneal dialysis compared to hemodialysis affect the risk of all-cause and infection-related hospitalizations in incident chronic dialysis patients?
Hazard Ratio: 1.27 (95% CI 1.07–1.5)
In incident chronic dialysis patients in Canada, peritoneal dialysis is associated with a higher risk of hospitalization in the first 7 days compared to hemodialysis, but hospitalization rates do not differ by modality thereafter.
Molnar et al. (2018) conducted a cohort in Incident chronic dialysis (n=38,369). Peritoneal dialysis vs. Hemodialysis was evaluated on All-cause hospitalization within the first 7 days after dialysis initiation (HR 1.27, 95% CI 1.07-1.50). Within the first 7 days after dialysis initiation, peritoneal dialysis was associated with a higher risk of all-cause hospitalization compared with hemodialysis (HR 1.27; 95% CI 1.07-1.50).
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