Key result
Poor knowledge of hypertension treatment is linked to ~19-fold higher odds of medication non-adherence.
Why the study?
Different factors contribute to non-adherence to antihypertensive medication, and identifying predictors of adherence among hypertensive adults was needed.
What are the predictors of non-adherence to anti-hypertensive medication among hypertensive adults in Ethiopia?
Case-Control (n=452)
No
What are the predictors of non-adherence to anti-hypertensive medication among hypertensive adults in Ethiopia?
Odds Ratio: 19 (95% CI 6.5–55.6)
p-value: p=<0.05
Female sex, lower educational status, and poor knowledge about hypertension treatment are significant predictors of non-adherence to antihypertensive medication in this Ethiopian cohort.
Supports knowledge interventions in Ethiopian hypertension care; leaves open effects on adherence in prospective studies.
Background: Uncontrolled hypertension can occur as a consequence of non-adherence to medication or dietary regimen.Different factors contribute to the non-adherence behaviour of the patients.Therefore, the aim of this study was to identify predictors of adherence to antihypertensive medication among hypertensive adults on follow up in Jimma University Specialized Hospital (JUSH), South West Ethiopia, 2016.Methods: Institution based case control study was planned to be conducted in JUSH on 488 hypertensive adults from March-April, 2016.Cases were those patients who score Morisky Medication Adherence Scale (MMAS) less than 80% and controls were those patients who score MMAS 80% and above.Consecutive sampling method was used to select the participants.A structured and pretested questionnaire was used.Data was entered into Epidata version 3.1 then exported to Stata version 13 for analysis.Multivariable logistic regression analysis was used to identify predictors of adherence to anti-hypertensive medication.Results: The number of cases and controls who participated in the study was 232 and 220 with response rate of 95% and 90% respectively.Factors significantly associated with non-adherence were being female patients (AOR=0.37,CI=0.17-0.80),educational status primary (AOR=0.27,CI=0.14-0.50),secondary (AOR=0.26,CI=0.10-0.69),and tertiary (AOR=0.17,CI=0.05-0.56)and knowledge about hypertension treatment (AOR=19.00,CI=6.50-55.60). Conclusion and recommendation:In this study predictors of non-adherence to antihypertensive medication were female sex, lower educational status and poor knowledge about hypertension treatment.Therefore health care providers should advise the patients to boost the knowledge of patients related to hypertension treatment.
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Kebede et al. (2018) conducted a case-control in Hypertension (n=452). Poor knowledge about hypertension treatment vs. Good knowledge about hypertension treatment was evaluated on Non-adherence to anti-hypertensive medication (MMAS < 80%) (AOR 19.00, 95% CI 6.50-55.60, p=<0.05). Poor knowledge about hypertension treatment was associated with a 19-fold increased odds of non-adherence to antihypertensive medication (AOR 19.00) compared to good knowledge.
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