Key result
Preeclampsia was associated with a significantly lower percent rhythm of pulse (0.27 vs 0.37) compared to white coat hypertension, suggesting abnormal circadian rhythms potentially due to sympathetic nerve disorders.
Why the study?
Does the circadian rhythm of blood pressure and pulse differ among pregnant women with preeclampsia, gestational hypertension, and white coat hypertension?
Observational (n=106)
Yes
Does the circadian rhythm of blood pressure and pulse differ among pregnant women with preeclampsia, gestational hypertension, and white coat hypertension?
Absolute Event Rate: 0.27% vs 0.37%
p-value: p=<0.05
Women with preeclampsia exhibit distinct disruptions in the circadian rhythm of both blood pressure and pulse compared to those with gestational hypertension, suggesting underlying sympathetic nerve dysfunction.
Hypertensive disorders of pregnancy (HDP) is defined as BP 140/90 mmHg, with or without proteinuria (300 mg/24 h), emerging after 20 weeks gestation, but resolving by up to 12 weeks postpartum It is mainly classified as preeclampsia (PE) or gestational hypertension (GH). GH is diagnosed in women who have hypertension without proteinuria, and conversely, PE is diagnosed when hypertension
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Yamamoto et al. (2018) conducted an observational in Hypertensive disorders of pregnancy (n=106). Preeclampsia vs. White coat hypertension was evaluated on Percent rhythm (PR) of pulse (p=<0.05). Preeclampsia was associated with a significantly lower percent rhythm of pulse (0.27 vs 0.37) compared to white coat hypertension, suggesting abnormal circadian rhythms potentially due to sympathetic nerve disorders.
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