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June 22, 2020Baylor University Medical Center ProceedingsOpen Access

Among 170 patients, valve-sparing aortic root replacement yielded higher combined freedom from death and reoperation compared to bioprosthetic or mechanical Bentall procedures.

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Why the study?

Does valve-sparing aortic root replacement improve freedom from recurrent aortic insufficiency, reoperation, or death compared to the Bentall procedure in patients with aortic root disease?

Population

170 patients with aortic root disease undergoing root replacement at a single center between November 2007…

Comparison

Valve-sparing aortic root replacement vs Bentall procedure, including bioprosthetic…

Design

Cohort

Key result

Among 170 patients, valve-sparing aortic root replacement yielded higher combined freedom from death and reoperation compared to bioprosthetic or mechanical Bentall procedures.

Authors

MHMohanad HamandiCNCE NwaforRBRonald Baxter

Discussion

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Member takes

Overview

Valve-sparing root replacement was associated with better outcomes in selected patients; leaves open whether it should be preferred over Bentall without randomized confirmation.

Study Design

Type

Cohort (n=170)

Multicenter

No

Structured PICO

Does valve-sparing aortic root replacement improve freedom from recurrent aortic insufficiency, reoperation, or death compared to the Bentall procedure in patients with aortic root disease?

P
Population
170 patients with aortic root disease who underwent bioprosthetic Bentall, mechanical Bentall, or valve-sparing aortic root replacement.
E
Exposure
Valve-sparing aortic root replacement (VSRR) (n=71)
C
Comparator
Bentall procedure, including bioprosthetic Bentall (BB) (n=36) and mechanical Bentall (MB) (n=63)
O
Outcome
Composite endpoint of freedom from recurrent aortic insufficiency, reoperation, or deathcomposite

Valve-sparing root replacement offers improved combined freedom from death and reoperation compared to Bentall procedures, though Bentall remains necessary for more severe or emergent cases.

Cite This Study

Hamandi et al. (2020) conducted a cohort in aortic root disease (n=170). Valve-sparing aortic root replacement (VSRR) vs. Bioprosthetic Bentall (BB) and mechanical Bentall (MB) was evaluated on Composite endpoint of freedom from recurrent aortic insufficiency, reoperation, or death. Among 170 patients, valve-sparing aortic root replacement yielded higher combined freedom from death and reoperation compared to bioprosthetic or mechanical Bentall procedures.

synapsesocial.com/papers/6ab0dbf9e440a2ddc0ec4df8https://doi.org/10.1080/08998280.2020.1771163
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Repair of aortic root in patients with aneurysm or dissection: comparing the outcomes of valvesparing root replacement with those from the Bentall procedure2013 · 18 citations
  2. 2Comparing outcomes between valve-sparing root replacement and the Bentall procedure in proximal aortic aneurysms: systematic review and meta-analysis2019 · 32 citations
  3. 3Bentall versus valve-sparing aortic root replacement for root pathology with moderate-to-severe aortic insufficiency: a propensity-matched analysis2023 · 14 citations
  4. 4Comparison of Outcomes between Valve-Sparing Root Replacement and the Bentall Procedure in Acute Stanford Type A Aortic Dissection: A Single-Center Retrospective Cohort Study in South Korea2026
  5. 5Is valve-sparing root replacement a safe option in acute type A aortic dissection? A systematic review and meta-analysis2019 · 38 citations