Key result
Valve-sparing aortic root replacement was associated with significantly lower operative mortality compared to the Bentall procedure (OR 0.51; 95% CI 0.37-0.70; P<0.001).
Why the study?
In aortic root aneurysms, VSRR aims to ensure durable valve function without reintervention, whereas the Bentall procedure defers durability to a prosthesis but tends to have higher complications.
Does valve-sparing aortic root replacement improve survival and reduce complications compared to the Bentall procedure in patients with aortic root aneurysms?
Population
7313 patients with aortic root aneurysms
Comparison
Valve-sparing aortic root replacement vs Bentall procedure
Authors
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Supports VSRR preference to lower operative mortality when feasible; reinforces meta-analytic evidence but leaves open need for RCTs.
Meta-Analysis (n=7,313)
Does valve-sparing aortic root replacement improve survival and reduce complications compared to the Bentall procedure in patients with aortic root aneurysms?
Odds Ratio: 0.51 (95% CI 0.37–0.7)
p-value: p=< 0.001
Valve-sparing aortic root replacement is associated with lower operative mortality, better 5-year survival, and fewer complications compared to the Bentall procedure, without an increased risk of long-term reoperation.
Salmasi et al. (2019) conducted a meta-analysis in Aortic root aneurysms (n=7,313). Valve-sparing aortic root replacement (VSRR) vs. Bentall procedure was evaluated on Operative mortality (OR 0.51, 95% CI 0.37-0.70, p=< 0.001). Valve-sparing aortic root replacement was associated with significantly lower operative mortality compared to the Bentall procedure (OR 0.51; 95% CI 0.37-0.70; P<0.001).
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