Key result
Routine oral poliovirus vaccination must eventually end to prevent vaccine-associated paralysis and circulating vaccine-derived viruses.
Why the study?
New tools and strategies are needed to complete polio eradication and manage risks associated with oral poliovirus vaccine use after eradication.
Design
Review
Authors
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OPV cessation warranted post-eradication; leaves open optimal transition strategies to minimize vaccine-derived risks.
Highlights the necessity and prerequisites for discontinuing oral poliovirus vaccines after polio eradication to prevent vaccine-derived outbreaks.
Sutter et al. (2006) conducted a review in Poliomyelitis. Oral poliovirus vaccines (OPVs) was evaluated. Routine immunization with oral poliovirus vaccines must eventually be discontinued to prevent vaccine-associated paralytic poliomyelitis and circulating vaccine-derived polioviruses.
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