Key result
Intensified preventive care fails to reduce 10-year absolute cardiovascular risk compared to usual care.
Why the study?
The effectiveness of a structured collaboration in general practice to provide intensified preventive care for high cardiovascular risk patients in deprived neighbourhoods was uncertain.
Does intensified preventive care reduce 10-year absolute cardiovascular risk in high-risk patients in deprived neighborhoods?
Comparison
Intensified preventive care vs usual care
Design
Randomized controlled trial in three healthcare centres with 18 GPs
Follow-up
12 months
Authors
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Does not support intensified preventive care for 10-year CV risk reduction; leaves open whether refined strategies benefit selected patients.
RCT (n=275)
randomized
Yes
Does intensified preventive care reduce 10-year absolute cardiovascular risk in high-risk patients in deprived neighborhoods?
Mean Difference: 0.88 (95% CI -1.16–2.93)
Absolute Event Rate: 1.76% vs 2.27%
A structured, multidisciplinary primary care intervention did not significantly reduce 10-year cardiovascular risk beyond the improvements seen with usual care in high-risk patients from deprived neighborhoods.
Fakiri et al. (2008) conducted an RCT in high risk of developing cardiovascular diseases (n=275). Intensified preventive care vs. usual care was evaluated on 10-year absolute risk (Framingham risk equation) (MD 0.88%, 95% CI -1.16 to 2.93). Intensified preventive care did not significantly reduce 10-year absolute cardiovascular risk compared to usual care (difference in mean change 0.88%; 95% CI -1.16 to 2.93).
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