Syntheses of 1-Methyl-2-azathiabenzene 1-Oxide and 1-Methyl-4-azathiabenzene 1-Oxide Derivatives

1-Methyl-2-azathiabenzene 1-oxide derivatives are synthesized by the reaction of dimethylsulfoximine and ketenethioacetal derivatives.Reaction of dimethyloxosulfonium methylide with cyanamide derivatives affords 1-methyl-4-azathiabenzene 1-oxide derivatives.1 Previously, we reported the synthesis of 1-methyl-2-acylthiabenzene 1-oxide derivatives in good yields.There are much interests in the aromaticity and chemical behavior of azathiabenzene 1-oxides, new heterocyclic systems.Recently, several groups have been reported on the synthetic methods and characteristic properties for 2-azathiabenzene 1-oxides, which were prepared by the reaction of dimethylsul-3 foximine and ethoxyethylene2 or acylacetylene derivatives .