Key result
Rare BCOR-rearranged Ewing-like sarcoma in a two-year-old's nasal cavity provides new clinical insights.
Why the study?
Ewing-like sarcomas rarely occur in the nose, and no cases of nasal BCOR-rearranged Ewing-like sarcoma had been reported in the medical literature to date.
Case Report (n=1)
This case report provides the first documented instance of a nasal BCOR-rearranged Ewing-like sarcoma in a child, expanding the known clinical presentations of this rare disease.
Highlights rare pediatric nasal site; leaves open optimal diagnosis and management strategies for BCOR-rearranged sarcomas.
Ewing-like sarcomas (ELS) are round cell mesenchymal neoplasms that are highly aggressive to bone and/or soft tissue. However, they rarely occur in the nose, with no reported such cases in the medical literature to date. Here, we reported the case of a two-year-old Chinese boy who presented with a mass in the left nasal cavity. Surprisingly, the final histopathological diagnosis of the nasal mass was determined to be a subtype of ELS, BCOR-rearranged sarcoma. Therefore, we retrospectively analyzed the clinical data of this case and reviewed the relevant literature on ELS and BCOR-rearranged sarcoma. The purpose of this article is to provide new insights into the clinical characteristics of children with BCOR-rearranged Ewing-like sarcoma and to improve the understanding of this disease.
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Ji et al. (2022) conducted a case report in Nasal BCOR-rearranged Ewing-like Sarcoma (n=1). A rare case of BCOR-rearranged Ewing-like sarcoma was identified in the left nasal cavity of a two-year-old Chinese boy, providing new insights into its clinical characteristics.
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