Key result
Combined chemotherapy, surgery, and radiotherapy achieves complete recovery in rare sinonasal extraskeletal Ewing sarcoma.
Why the study?
Extraskeletal Ewings sarcoma of the sinonasal tract is very rare and requires differentiation from other small round cell tumors for appropriate treatment.
Case Report (n=1)
This case report highlights the rare occurrence of extraskeletal Ewing's sarcoma in the sinonasal tract and its successful treatment with a multimodal approach.
Rare sinonasal ES case expands differential for nasal masses; leaves open standardized multimodal protocols for extraskeletal head-neck disease.
Ewings sarcoma (ES) and primitive neuroectodermal tumor are closely related family of small round cell tumors seen in childhood and adolescence. The incidence of these tumors occurring in the head and neck region is just 2-7%. Mandible and maxilla are the most common sites, whereas involvement of the sinonasal tract is very rare. We report a case of extraskeletal ES of the sinonasal tract in a 29-year-old female who presented with nasal obstruction and epistaxis. The patient was treated with 14 cycles of chemotherapy, combined with surgery and radiotherapy with complete recovery. We present this case due to its rarity, to analyze the clinical, histopathological and immunohistochemical findings, so as to differentiate from other small round cell tumors of the sinonasal tract for appropriate treatment.
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Yeshvanth et al. (2012) conducted a case report in Extraskeletal Ewings sarcoma of the sinonasal tract (n=1). Chemotherapy, surgery, and radiotherapy was evaluated on Recovery. A 29-year-old female with rare extraskeletal Ewings sarcoma of the sinonasal tract achieved complete recovery following 14 cycles of chemotherapy combined with surgery and radiotherapy.
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