Key result
FDG-PET detects large-vessel inflammation in 100% of chronic periaortitis patients compared to controls.
Why the study?
The presence and extent of large-vessel inflammation in patients with chronic periaortitis using FDG-PET had not been evaluated.
Does FDG-PET imaging detect large-vessel inflammation in patients with chronic periaortitis compared to controls?
Population
7 patients with chronic periaortitis and 14 age- and sex-matched controls with malignancy
Comparison
FDG-PET imaging in chronic periaortitis patients vs controls with malignancy
Design
Consecutive case series with age- and sex-matched controls
Authors
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May support FDG-PET for vascular inflammation in chronic periaortitis; hypothesis-generating and requires prospective validation before clinical use.
Case-Control (n=21)
Does FDG-PET imaging detect large-vessel inflammation in patients with chronic periaortitis compared to controls?
Absolute Event Rate: 100% vs 0%
FDG-PET imaging effectively identifies large-vessel vasculitis involving the abdominal aorta and iliac arteries in patients with chronic periaortitis.
Salvarani et al. (2005) conducted a case-control in Chronic periaortitis (n=21). Chronic periaortitis vs. Age- and sex-matched controls with malignancy was evaluated on Vascular uptake in abdominal aorta and/or iliac artery. FDG-PET imaging revealed large-vessel inflammation in the abdominal aorta and/or iliac artery in 100% of patients with chronic periaortitis compared to 0% of controls.
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