Why the study?
Does (18)FDG-PET imaging detect increased cellular metabolism in the lungs and right ventricle of patients with pulmonary arterial hypertension compared to controls?
Population
14 patients with pulmonary hypertension (idiopathic and chronic thromboembolic) and 6 controls (total n=20).
Comparison
(18)FDG-PET/CT imaging of the thorax vs Controls without pulmonary hypertension
Design
Case-control
Authors
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Supports FDG-PET for metabolic assessment in IPAH; hypothesis-generating and should not yet change practice.
Does (18)FDG-PET imaging detect increased cellular metabolism in the lungs and right ventricle of patients with pulmonary arterial hypertension compared to controls?
(18)FDG-PET imaging demonstrates increased cellular metabolism in the lung parenchyma and right ventricle of patients with idiopathic pulmonary arterial hypertension, suggesting its potential as a surrogate marker for disease activity.
Hagan et al. (2011) studied this question.
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