Why the study?
Does right ventricular 18F-FDG uptake correlate with hemodynamics and predict survival in patients with IPAH and CHD-PAH?
Does right ventricular 18F-FDG uptake correlate with hemodynamics and predict survival in patients with IPAH and CHD-PAH?
Increased right ventricular 18F-FDG uptake correlates with pulmonary vascular resistance, serves as a marker of poor prognosis in idiopathic pulmonary arterial hypertension, and decreases with effective targeted therapy.
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RV/LV FDG uptake >1.20 was associated with lower IPAH survival; leaves open whether FDG-PET refines risk stratification or monitors therapy response.
Fang et al. (2012) studied this question.
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