Key result
Patients with pulmonary arterial hypertension had significantly higher right-to-left ventricular FDG uptake ratios than controls, correlating strongly with pulmonary artery systolic pressure (r=0.87, P<0.05).
Why the study?
Does F-18 FDG PET imaging reveal increased right ventricular glucose metabolism in patients with pulmonary arterial hypertension compared to healthy controls?
Population
23 patients with pulmonary arterial hypertension (PAH) and 16 healthy controls (n=39)
Comparison
F-18 fluorodeoxyglucose positron emission… vs Healthy controls
Design
Case-control
Authors
Loading...
RV FDG uptake associated with PAH severity on PET; hypothesis-generating, requires prospective validation before clinical use.
Case-Control (n=39)
Does F-18 FDG PET imaging reveal increased right ventricular glucose metabolism in patients with pulmonary arterial hypertension compared to healthy controls?
p-value: p=<0.05
Increased right ventricular glucose metabolism on FDG-PET in PAH patients correlates with elevated pulmonary pressures, reduced exercise capacity, and right ventricular dysfunction.
Can et al. (2011) conducted a case-control in Pulmonary Arterial Hypertension (n=39). Pulmonary arterial hypertension vs. Healthy controls was evaluated on Right to left ventricular FDG uptake ratio (p=<0.05). Patients with pulmonary arterial hypertension had significantly higher right-to-left ventricular FDG uptake ratios than controls, correlating strongly with pulmonary artery systolic pressure (r=0.87, P<0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: