Key result
Epidural ropivacaine is linked to ~171% more patients achieving significant pain relief vs intramuscular tramadol.
Why the study?
Adequate analgesia during labour positively influences labour course, but comparative data on parenteral tramadol versus epidural ropivacaine for labour analgesia are limited.
Does epidural ropivacaine improve pain relief and maternal outcomes compared to intramuscular tramadol in women during labour?
Does epidural ropivacaine improve pain relief and maternal outcomes compared to intramuscular tramadol in women during labour?
Absolute Event Rate: 92% vs 34%
p-value: p=0.000
Epidural ropivacaine provides superior pain relief and patient satisfaction compared to intramuscular tramadol for labour analgesia, without adversely affecting labour duration or delivery mode.
Epidural ropivacaine was associated with superior analgesia and satisfaction versus intramuscular tramadol; leaves open whether outcomes differ in larger randomized cohorts.
Background: The pain of childbirth is one of the most severe types of pain that a woman experiences in her lifetime. Adequate analgesia during labour has a positive influence on the course of labour. For labor analgesia several non-pharmacologic and pharmacologic methods are adopted. The objective of the study is to compare parenteral tramadol and epidural ropivacaine with regard to maternal and labour outcome.Methods: This prospective, comparative, interventional clinical study was conducted at Kasturba Hospital, Daryaganj, Delhi, on the patients admitted in the labour room of the hospital during the period of September 2014 to July 2015. Various parameters of maternal condition and labour outcome in each group were monitored and compared. These included the degree of pain relief and patient satisfaction, duration of 1st and 2nd stage of labour, mode of delivery and duration of third stage and any third stage complication like post-partum haemorrhage (PPH) and retained placenta and side effect profile of both the drugs.Results: Epidural ropivacaine has significantly better analgesic efficacy and faster onset of action as compared to I/M tramadol and patients in epidural group were significantly better satisfied. Ninety-two percent of patients in tramadol group and eighty eight percent in epidural group underwent normal delivery. Duration of the three stages of labour, complications of third stage and side effect profile in both the groups were comparable.Conclusions: Maternal outcome in labour analgesia is similar with 100 mg I/M tramadol and epidural ropivacaine. There is no significant difference between duration of labour, rate of LSCS, incidence of instrumental delivery and neonatal outcome in the two modes of analgesia. Analgesic efficacy with epidural ropivacaine seems to be better compared to intramuscular tramadol.
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Lamba et al. (2016) studied Labour pain (n=100). Epidural ropivacaine vs. Intramuscular tramadol (100 mg) was evaluated on Significant fall in Visual Analogue Scale (VAS) score (≤ 5) (p=0.000). Epidural ropivacaine provided significantly better analgesic efficacy compared to intramuscular tramadol, with 92% of patients achieving a significant fall in VAS score versus 34% in the tramadol group (p=0.000).
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