Why the study?
The cost-effectiveness of different groups of antihypertensive therapies for effective clinical and economic management was evaluated.
What is the comparative cost-effectiveness and clinical efficacy of different classes of antihypertensive therapies in reducing blood pressure?
Cross-Sectional (n=81)
No
What is the comparative cost-effectiveness and clinical efficacy of different classes of antihypertensive therapies in reducing blood pressure?
Different classes of antihypertensives offer specific clinical and economic advantages, with ACEIs being cost-effective for SBP reduction and CCBs for DBP maintenance.
May support class-specific antihypertensive selection; leaves open randomized confirmation of cost-effectiveness.
Objective: The study objective is to evaluate among the different groups of antihypertensive for their cost-effectiveness and to provide information about the effective management of hypertensives both clinically and economically. Methods: This study involves 81 patients aged 18–80 years on antihypertensive treatment who were enrolled from December to May with daily dose calculation. It is performed to analyze cost-effectiveness in the management of clinical condition. Data collection form to be entered with age, sex, food habits, occupational status, clinical data, and drugs was used for treatment. Incremental cost-effectiveness ratio is calculated based on the incremental cost for “per mmHg” reduction and cost for “per patient” reaching target blood pressure (BP). Result: Angiotensin receptor blockers (ARBs) show a significant average reduction of systolic BP (SBP) and beta-blockers (BBs) show an average reduction of diastolic BP (DBP). Angiotensin-converting enzyme inhibitors (ACEIs) are cost effective in SBP and calcium channel blockers are cost effective in maintaining DBP. Conclusion: ARBs, BBs, and ACEIs show the effective management of hypertensives both clinically and economically.
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A et al. (2018) conducted a cross-sectional in Hypertension (n=81). Antihypertensive therapy (ARBs, BBs, ACEIs, CCBs) vs. Between-group comparisons was evaluated on Cost-effectiveness based on cost per mmHg reduction and cost per patient reaching target blood pressure.
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