Key result
Hypertension, increased heart weight, and diabetes are linked to worse cerebral atherosclerosis in adult Nigerians.
Why the study?
Factors associated with cerebral atherosclerosis in Nigerian Africans and its relationship to selected diseases were not well characterized.
Population
465 autopsied adult Nigerians
Comparison
Nigerian population vs Minnesota Caucasian populations
Design
Observational pathological study
Authors
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Greater atherosclerosis severity in hypertensive Nigerians versus Caucasians; leaves open ethnic-specific stroke prevention strategies pending prospective data.
Observational (n=465)
Yes
The relatively low frequency of cerebrovascular disease in Nigerians may be explained by a low degree of cerebral atherosclerosis and relatively short duration of hypertension before death.
Williams et al. (1975) conducted an observational in Cerebral atherosclerosis (n=465). Hypertension vs. Normotension was evaluated on Cerebral atherosclerosis. Hypertension, increased heart weight, and diabetes mellitus were associated with increased frequency and severity of cerebral atherosclerosis, which was present in 13% of autopsied adult Nigerians.
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