Key result
Severe leptospirosis is linked to septic cardiomyopathy and diffuse myocardial calcifications requiring multimodality imaging.
Why the study?
Cardiac involvement in leptospirosis is uncommon and its pathophysiology, including diffuse myocardial calcifications, is not well understood.
Case Report (n=1)
No
Severe leptospirosis can cause septic cardiomyopathy and diffuse myocardial calcifications, highlighting the importance of multimodality imaging and long-term follow-up for cardiac recovery.
Myocardial calcifications in leptospirosis may signal arrhythmia risk; single case report leaves open clinical relevance and need for prospective data.
Severe leptospirosis is defined by multiple organ failure. Cardiac involvement is an uncommon complication in patients with leptospirosis, and the pathophysiology of it is not well understood. Diffuse myocardial calcifications connected with sepsis are infrequent, and their effect on heart function is hard to predict. They can lead to conduction disorders and arrhythmias, thereby causing sudden death. Myocardial calcifications are usually revealed incidentally by radiological investigations such as computed tomography (CT) scan in patients with or after sepsis and are commonly unidentified in practice because most cases progress gradually. This case report involves a 51-year-old male who presented to the emergency department with sepsis. The patient was diagnosed with leptospirosis, causing septic cardiomyopathy and diffuse calcifications of the myocardium of the left ventricle. This case highlights the importance of multimodality imaging and a multidisciplinary approach to diagnoses since early recognition and treatment are essential. Follow-up of such patients is necessary to monitor the systolic function of the left ventricle and cardiac arrhythmia.
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Lesjak et al. (2023) conducted a case report in Leptospirosis with septic cardiomyopathy (n=1). Leptospirosis was evaluated on Development of diffuse myocardial calcifications and septic cardiomyopathy. Severe leptospirosis can lead to septic cardiomyopathy and diffuse myocardial calcifications, highlighting the importance of multimodality imaging for diagnosis and monitoring.
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