OBJECTIVE: To investigate the relationship between the plasma antidiuretic hormone (p-ADH) level, electrocochleogram (ECoG), and the glycerol test in patients with endolymphatic hydrops (ELH). PATIENTS AND METHODS: The subjects were 60 patients, including 51 with Ménière's disease (except for cochlear Ménière's disease), 7 with delayed ELH, and 2 with syphilitic ELH. The time period for measurements of the p-ADH level, ECoG and the glycerol test was within 4 weeks. RESULTS: 13 patients showed positive results for all tests. 58 patients showed positive results for at least one of three tests. Only 2 patients showed negative results for all tests. CONCLUSION: The p-ADH level, ECoG and the glycerol test show different selectivity of ELH detection. It is useful to perform all three tests to diagnose ELH.
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Taguchi et al. (2009) studied this question.
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