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Reports successful treatment of intracardiac thrombosis using low-dose recombinant tissue plasminogen activator during liver transplantation, indicating early detection supports rapid clot breakdown.
Intracardiac thrombosis and pulmonary embolism are uncommon complications during liver transplantation but carry a high mortality rate. We report the successful use of low-dose recombinant tissue plasminogen activator (0.5-4 mg) administration in 4 patients. Early diagnosis through transesophageal echocardiography and pulmonary artery catheterization may have contributed to the rapid thrombolysis.
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Boone et al. (2010) studied this question.
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