Key result
Low-dose prolonged infusion of tissue plasminogen activator achieved hemodynamic stabilization and complete thrombus resolution in a 95-year-old woman with acute pulmonary embolism.
Case Report (n=1)
Low-dose prolonged infusion of tissue plasminogen activator successfully stabilized a 95-year-old patient with acute pulmonary embolism and massive thrombus.
May support low-dose prolonged tPA in select elderly PE; leaves open need for controlled trials.
Acute pulmonary embolism is an important emergency disease which frequently results in life-threatening complication. Systemic fibrinolysis is recommended as standard, first-line therapy in patients with massive pulmonary embolism. In the case described in this report, a 95-year-old woman was treated with low-dose prolonged infusion of tissue plasminogen activator for acute pulmonary embolism and mobile thrombus in the main pulmonary artery and right pulmonary artery. On the basis of echocardiographic findings, acute thrombolysis with low-dose prolonged infusion of tissue plasminogen activator was performed resulting in hemodynamic stabilization of the patient and complete resolution of the pulmonary artery thrombus.
No takes yet. Share an insight, caveat, or question.
Yıldız et al. (2012) conducted a case report in Acute pulmonary embolism (n=1). Tissue plasminogen activator was evaluated on Hemodynamic stabilization and resolution of pulmonary artery thrombus. Low-dose prolonged infusion of tissue plasminogen activator achieved hemodynamic stabilization and complete thrombus resolution in a 95-year-old woman with acute pulmonary embolism.