Why the study?
The impact of three-day positive water balance during fluid therapy on survival of ICU patients with polytrauma was unclear.
Does a positive water balance >4075 ml over 3 days increase mortality in ICU patients with polytrauma and hypovolemic shock?
Observational (n=40)
No
Does a positive water balance >4075 ml over 3 days increase mortality in ICU patients with polytrauma and hypovolemic shock?
Relative Risk: 5.1 (95% CI 0.773–0.992)
p-value: p=<0.005
A positive water balance exceeding 4075 ml over the first 3 days in the ICU is a strong predictor of mortality in patients with polytrauma and hypovolemic shock.
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Orlov et al. (2018) conducted an observational in Polytrauma and hypovolemic shock (n=40). Positive water balance > 4075 ml over 3 days vs. Positive water balance < 4075 ml over 3 days was evaluated on 30-day ICU mortality (RR 5.1, 95% CI 0.773-0.992, p=<0.005).
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