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July 27, 2016BMC Public HealthOpen Access

Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) – a Pan Canadian cohort study

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Key result

CAHHM cohort protocol outlines MRI-based investigation of socio-environmental factors on cardiovascular and cognitive health.

  • n=7,000

Why the study?

The association of socio-environmental and contextual factors with cardiovascular risk factors, subclinical vascular disease, and chronic disease outcomes in a multi-ethnic Canadian population is not fully understood.

How do socio-environmental and contextual factors associate with cardiovascular risk factors, subclinical vascular disease, and chronic disease outcomes in Canadian adults?

Population

Adults aged 35 to 69 years from existing cohorts and a new First Nations Cohort in Canada

Comparison

Detailed assessment of health behaviours, cognitive function, environments, health services access, physical measures, and MRI imaging

Design

Pan-Canadian prospective multi-ethnic cohort study

Authors

SASonia S. AnandVascular MedicineJTJack V. TuHeart Failure & TransplantPAPhilip AwadallaOntario Institute for Cancer Research

Discussion

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Member takes

Implication

Provides a multi-ethnic Canadian platform to examine contextual CVD determinants; leaves open specific associations pending prospective follow-up.

Study Design

Type

Cohort (n=7,000)

Multicenter

Yes

Structured PICO

How do socio-environmental and contextual factors associate with cardiovascular risk factors, subclinical vascular disease, and chronic disease outcomes in Canadian adults?

P
Population
A planned prospective cohort of approximately 7,000 adults aged 35 to 69 years in Canada, designed to investigate the impact of socio-environmental factors on cardiovascular and cognitive health using MRI.
E
Exposure
Detailed assessment of health behaviours, cognitive function, local environments, health services access, physical measures, and magnetic resonance imaging (MRI) of the brain, heart, carotid artery, and abdomen
O
Outcome
Association of socio-environmental and contextual factors with cardiovascular risk factors, subclinical vascular disease, and cardiovascular and other chronic disease outcomes

The CAHHM study is a pan-Canadian prospective cohort designed to evaluate the impact of socio-environmental factors on cardiovascular risk and subclinical vascular disease using detailed assessments and MRI.

Limitations

  • Coordinating recruitment from 7 existing cohorts and a new First Nations cohort
  • Facilitating MRI scanning in urban, rural, and remote regions
  • Conducting record linkage for clinical events across multiple provinces

Cite This Study

Anand et al. (2016) conducted a cohort in Cardiovascular disease and cognitive dysfunction (n=7,000). Socio-environmental and contextual factors was evaluated on Composite of MI, stroke, angioplasty, percutaneous coronary interventions, coronary artery bypass graft surgery, other chronic disease outcomes, and death. The Canadian Alliance for Healthy Hearts and Minds (CAHHM) is a prospective cohort study protocol designed to investigate the impact of socio-environmental factors on cardiovascular and cognitive health using MRI.

synapsesocial.com/papers/6ab1f3ab95b6c8d86ac08c51https://doi.org/10.1186/s12889-016-3310-8

Topics

Women and heart disease
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