Key result
Physical training improves exercise capacity and quality of life compared to controls.
Why the study?
Patients with coronary syndrome X have exercise-induced chest pain despite normal coronary arteries and represent a therapeutic challenge with residual morbidity and reduced quality of life, necessitating investigation of physiotherapeutic interventions.
Does physical training or relaxation therapy improve exercise capacity and quality of life in women with coronary syndrome X?
RCT (n=24)
Single-blind
randomly assigned
Does physical training or relaxation therapy improve exercise capacity and quality of life in women with coronary syndrome X?
In women with coronary syndrome X, physical training improves both exercise capacity and quality of life, whereas relaxation therapy improves only quality of life.
Answers are grounded in this paper and cite their sources.
Physical training merits first-line consideration in women with coronary syndrome X; extends RCT evidence for exercise in non-obstructive angina.
BACKGROUND AND PURPOSE: New types of illness are being identified continuously. Owing to the demands for evidence-based practice, physiotherapeutic interventions need to be investigated scientifically prior to application in a new patient population. Coronary syndrome X (syndrome X) is a chronic pain disorder with exercise-induced chest pain despite angiographically normal coronary arteries. Patients with syndrome X constitute a therapeutic problem with considerable residual morbidity associated with functional limitation and reduced quality of life. Therefore, the aim of the present study was to investigate the effects of physical training and relaxation therapy on exercise capacity and quality of life in patients with syndrome X. METHOD: A single-blind, randomized controlled trial design was used. Twenty-four female patients aged 41-65 years were randomly assigned to three groups: A, B and C. All groups were similar at baseline for physical fitness level. Group A performed physical training for eight weeks at 50% of baseline VO2max and group B participated in relaxation therapy for eight weeks. Group C acted as control subjects without any intervention. Before and after the eight-week periods, subjects were assessed by means of several measures of exercise capacity and quality of life. RESULTS: The measured variables did not change in the control group during the eight weeks. VO2max (< 0.02), work rate (< 0.002) and distance walked during six minutes (< 0.003) increased only after physical training. The tolerated exertion during six minutes of walking (< 0.05) and the health-related quality of life, measured both by the Stress and Crisis Inventory (SCI) and the Sickness Impact Profile (SIP) (< 0.04), improved after both physical training and relaxation therapy. The general coping capacity, measured by the Sense of Coherence (SOC) questionnaire, remained unchanged in all the groups. CONCLUSIONS: Female patients with syndrome X benefit from physical training in terms of exercise capacity and quality of life and from relaxation therapy in terms of quality of life.
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Tyni‐Lenné et al. (2002) conducted an RCT in Coronary syndrome X (n=24). Physical training and relaxation therapy vs. No intervention was evaluated on Exercise capacity and quality of life (p=< 0.02). Physical training improved VO2max (P<0.02), work rate (P<0.002), and walk distance (P<0.003), while both physical training and relaxation therapy improved quality of life (P<0.04).
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