Key result
An 8-week autogenic training program significantly reduced symptom frequency compared with a symptom diary control (1.66 vs 8.04; P<0.001) in women with cardiac syndrome X.
Why the study?
Does an 8-week autogenic training program improve symptom frequency and severity in women with cardiac syndrome X?
RCT (n=53)
Does an 8-week autogenic training program improve symptom frequency and severity in women with cardiac syndrome X?
Absolute Event Rate: 1.66% vs 8.04%
p-value: p=<0.001
An 8-week autogenic training program significantly reduces symptom frequency and improves quality of life in women with cardiac syndrome X.
Supports autogenic training for symptom management in cardiac syndrome X; extends RCT evidence for nonpharmacologic approaches in microvascular angina.
OBJECTIVES: To explore autogenic training (AT) as a treatment for psychological morbidity, symptomology, and physiological markers of stress among women with chest pain, a positive exercise test for myocardial ischemia, and normal coronary arteries (cardiac syndrome X). DESIGN: Fifty-three women with cardiac syndrome X (mean +/- SD age, 57.1 +/- 8 years) were randomized to an 8-week AT program or symptom diary control. Symptom severity and frequency, Hospital Anxiety and Depression Scale, Spielberger State-Trait Anxiety Inventory, Cardiac Anxiety Questionnaire (CAQ), and Ferrans and Powers Quality of Life Index (QLI), blood pressure, heart rate, electrocardiogram, and plasma catecholamines were measured before and after intervention and at the 8-week follow-up. RESULTS: Women who underwent AT had improved symptom frequency (8.04 +/- 10.08 vs 1.66 +/- 2.19, P < 0.001) compared with control women and reduced symtom severity (2.08 +/- 1.03 vs 1.23 +/- 1.36, P = 0.02) and frequency (6.11 +/- 3.17 vs 1.66 +/- 2.19, P < G 0.001) post-AT compared with baseline within group. Within-group improvements among women who underwent AT include QLI health functioning (17.80 +/- 5.74 vs 19.41 +/- 5.19, P = 0.04) and CAQ fear (1.53 +/- 0.61 vs 1.35 +/- 0.56, P = 0.02) post-AT and QLI health functioning (17.80 +/- 5.74 vs 20.09 +/- 5.47, P = 0.01), CAQ fear (1.53 +/- 0.61 vs 1.30 +/- 0.67, P = 0.002), CAQ total (1.42 +/- 0.54 vs 1.29 +/- 0.475, P = 0.04), Spielberger State-Trait Anxiety Inventory trait anxiety (42.95 +/- 11.19 vs 38.68 +/- 11.47, P = 0.01), and QLI quality of life (20.67 +/- 5.37 vs 21.9 +/- 4.89, P = 0.02) at follow-up. CONCLUSION: An 8-week AT program improves symptom frequency, with near-significant improvements in symptom severity in women with cardiac syndrome X.
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Asbury et al. (2009) conducted an RCT in Cardiac syndrome X (n=53). Autogenic training vs. Symptom diary control was evaluated on Symptom frequency (p=<0.001). An 8-week autogenic training program significantly reduced symptom frequency compared with a symptom diary control (1.66 vs 8.04; P<0.001) in women with cardiac syndrome X.
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