Key result
Exercise improves LVEF by ~2% versus conventional care in dialysis patients.
Why the study?
Prolonged dialysis leads to heart failure, the leading cause of death among dialysis patients, and exercise has been shown to improve heart function indicators.
Do exercise interventions improve left ventricular ejection fraction in dialysis patients with cardiac function disorders?
Population
Dialysis patients with cardiac function disorders
Comparison
Exercise interventions vs conventional care
Design
Meta-analysis of studies published between January 2010 and July 2024
Authors
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Supports integrating exercise into dialysis care to lower heart failure risk; extends Level 1 evidence for cardiac benefits in this population.
Meta-Analysis (n=1,088)
Do exercise interventions improve left ventricular ejection fraction in dialysis patients with cardiac function disorders?
Mean Difference: 2 (95% CI 1.15–2.84)
p-value: p=<0.001
Exercise interventions, particularly combined aerobic and resistance training, significantly improve LVEF and reduce LVMI in dialysis patients with cardiac function disorders.
Liu et al. (2025) conducted a meta-analysis in Cardiac function disorders in dialysis patients (n=1,088). Exercise (aerobic, resistance, or combined) vs. Conventional care (no exercise) was evaluated on Left ventricular ejection fraction (LVEF) (MD 2.00, 95% CI 1.15-2.84, p=<0.001). Exercise significantly increased the left ventricular ejection fraction in dialysis patients compared to conventional care (MD 2.00, p < 0.001).
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