Key result
Dual-color upconversion nanoparticles with magnetic bioseparation enable sensitive simultaneous detection of EV-71 and CV-A16.
Why the study?
A sensitive and selective detection method for EV-71 and CV-A16 is needed to improve diagnostic capabilities.
A novel fluorescence analysis using dual-colour upconversion nanoparticles and magnetic bioseparation enables sensitive detection of EV-71 and CV-A16.
Facilitates sensitive EV-71/CV-A16 detection; extends biosensing approaches but leaves open clinical translation.
We highlight a novel fluorescence analysis for sensitive and selective detection of EV-71 and CV-A16 by combining labelling technology based on dual-colour upconversion fluorescence nanoparticles (UCNPs) with magnetic bioseparation and concentration technology based on magnetite nanoparticles (MNPs).
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Wu et al. (2012) studied this question. Dual-colour upconversion fluorescence nanoparticles combined with magnetic bioseparation enable sensitive and selective simultaneous detection of enterovirus 71 and coxsackievirus A16.
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