Key result
Pericardial closure worsens hemodynamics without reported adverse clinical outcomes in open heart surgery.
Why the study?
The adverse haemodynamic impact of pericardial closure in open heart surgery is known, but its effect on clinical outcomes remains unclear.
Does closing the pericardium cause adverse effects in patients undergoing open heart surgery?
Systematic Review
Does closing the pericardium cause adverse effects in patients undergoing open heart surgery?
While pericardial closure in open heart surgery has an adverse haemodynamic impact, it has not been linked to adverse clinical outcomes.
A best evidence topic in Cardiothoracic Surgery was written according to a structured protocol. The question addressed was in open heart surgery is there any adverse effect to closing the pericardium? Altogether 240 publications were found using the reported search of which 8 were deemed to be relevant to answer the clinical question. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes, results, and study weaknesses of these papers are tabulated. We conclude that the adverse haemodynamic impact of pericardial closure is confirmed in several studies, however, no study has yet reported an adverse clinical outcome due to the closure of the pericardium.
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Mohamad N Bittar (2005) conducted a systematic review in Open heart surgery. Pericardial closure vs. Leaving the pericardium open was evaluated on Adverse haemodynamic impact and adverse clinical outcomes. Pericardial closure during open heart surgery has a confirmed adverse haemodynamic impact, but no study has yet reported an adverse clinical outcome due to the closure.
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