Key result
In two patients with ICDs, induced ventricular fibrillations showed varying amplitudes of local electrograms, with fine ventricular electrograms leading to undersensing and delayed shock delivery.
Why the study?
The amplitude of the ventricular electrogram during ventricular fibrillation may vary and cause undersensing or unsuccessful defibrillation by ICDs, requiring investigation.
Case Report (n=2)
No
Small amplitude ventricular electrograms during ventricular fibrillation can lead to ICD undersensing and delayed shock delivery, highlighting the need for careful evaluation of ventricular activation amplitude.
An implantable cardioverter defibrillator (ICD) was implanted in 2 patients with ventricular tachyarrhythmia related to old myocardial infarction, and defibrillation tests were attempted at the time of ICD implantation and at 2 or 4 weeks after the operation. Ventricular fibrillation (VF) was induced by T-wave shocks, but the amplitude of the ventricular electrogram was different in each VF. In most of the VFs with large ventricular electrograms, the local activity was appropriately detected. However, many undersensed beats were observed in other VFs that had fine ventricular electrograms and a longer time was needed before delivering the shock. The amplitude of the ventricular electrogram might be small in some cases of VF and this might result in undersensing and/or unsuccessful defibrillation. Close attention must be paid to the amplitude of ventricular activation in each VF to avoid possible difficulty in ICD therapy.
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Chinushi et al. (1999) conducted a case report in Ventricular tachyarrhythmia related to old myocardial infarction (n=2). Implantable cardioverter defibrillator (ICD) was evaluated on Amplitude of ventricular electrogram during induced ventricular fibrillation and sensing by ICD. In two patients with ICDs, induced ventricular fibrillations showed varying amplitudes of local electrograms, with fine ventricular electrograms leading to undersensing and delayed shock delivery.
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