Key result
A 16-cm chest wall leiomyosarcoma was successfully treated with preoperative chemotherapy, which induced 50% tumor necrosis, followed by radical resection and two-stage reconstruction, resulting in recurrence-free survival at 3 years and 5 months.
Case Report (n=1)
Radical resection after preoperative chemotherapy can be an effective treatment strategy for large chest wall leiomyosarcomas.
Supports neoadjuvant chemotherapy and staged reconstruction for rare large chest wall sarcomas; hypothesis-generating given single-case design.
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Sawano et al. (2021) conducted a case report in Leiomyosarcoma of the chest wall (n=1). Preoperative chemotherapy and radical resection was evaluated on Recurrence-free survival. A 16-cm chest wall leiomyosarcoma was successfully treated with preoperative chemotherapy, which induced 50% tumor necrosis, followed by radical resection and two-stage reconstruction, resulting in recurrence-free survival at 3 years and 5 months.
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