Copper Oxide Microstructures with Hemisphere Pineapple Morphology for Selective Amperometric Determination of Vitamin C (L‐ascorbic Acid) in Human Fluids

Control over morphology, surface composition and porosity of nanostructured metal oxides play a significant role in designing a selective and sensitive electrochemical sensor. Herein, we explore a simple synthesis route for control fabrication of porous CuO hemisphere pineapple‐like morphology without using any structure directing agents. The results show that, CuO hemispheres are consisting of self‐assembled porous nanoneedles. The as‐prepared CuO hemispheres were simply drop‐casted onto graphite screen‐printed electrodes (CuO‐SPEs). Then, it was tested for determination of ascorbic acid in Britton Robinson (B. R.) buffer of pH 7.4. Interestingly, the CuO‐SPE provides robust, sensitive, fast response and selective enzyme‐less ascorbic acid sensor. These superior features allowed efficient, costless, stable, and precise non‐enzymatic detection of ascorbic acid in urine samples avoiding interferences and enhancing the accuracy of urinalysis examination.