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December 1, 2015Suez Canal Veterinary Medicine Journal SCVMJOpen Access

Genetic Characterization of Foot and Mouth Disease Virus Serotype A Circulating in Eastern Egypt

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Key result

VP1 sequencing of FMDV type A isolates from Egyptian cattle and buffaloes revealed 94.9-97.1% identity to Iranian strains, suggesting evolution from FMDV circulating in Iran.

Population

82 pooled tongue epithelia and vesicular fluids samples collected from cattle and buffaloes in 4…

Design

Preclinical

Authors

MEMohamed ElshahidyMSMohamed N. F. ShaheenEEEsraa El-Sadek

Discussion

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Overview

May inform regional FMDV surveillance in Egypt; leaves open direct transmission routes from Iran.

Study Design

Type

Observational (n=82)

Multicenter

Yes

Structured PICO

P
Population
82 pooled samples from cattle and buffaloes in 4 Egyptian governorates collected between March 2013 and December 2014.
E
Exposure
Isolation and genetic characterization (RT-PCR, ELISA, sequencing)
O
Outcome
Genetic characterization and phylogenetic relationship of FMDV type A isolates

FMDV type A circulating in Eastern Egypt between 2013 and 2014 is closely related to Iranian strains, which is important for formulating effective control strategies.

Cite This Study

Elshahidy et al. (2015) conducted an observational in Foot-and-Mouth Disease (n=82). FMDV type A was evaluated on VP1 sequence identity to other strains. VP1 sequencing of FMDV type A isolates from Egyptian cattle and buffaloes revealed 94.9-97.1% identity to Iranian strains, suggesting evolution from FMDV circulating in Iran.

synapsesocial.com/papers/6ab22b565da0d48688c51555https://doi.org/10.21608/scvmj.2015.64628
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Foot and Mouth Disease in Animals in Sharkia Governorate - Egypt2010 · 14 citations
  2. 2Evolutionary analysis of serotype A foot-and-mouth disease viruses circulating in Pakistan and Afghanistan during 2002–20092011 · 53 citations
  3. 3Phylogenomics and Molecular Evolution of Foot-and-Mouth Disease Virus2011 · 32 citations
  4. 4Establishment of persistent infection with foot-and-mouth disease virus in BHK-21 cells2011 · 52 citations