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February 1, 2019Veterinary WorldOpen Access

Foot-and-mouth disease outbreaks in Egypt during 2013-2014: Molecular characterization of serotypes A, O, and SAT2

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Key result

During the 2013-2014 foot-and-mouth disease outbreaks in Egypt, serotype O was the predominant circulating strain (70.45%), followed by serotype A (20.45%) and SAT2 (9.10%).

Why the study?

Continuous mutations and emerging new topotypes of FMDV lead to occasional vaccination failures in endemic Egypt, prompting genetic characterization of circulating strains during the 2013-2014 outbreaks.

Population

51 oral tissue samples from cattle and buffaloes with suspected FMD in Egypt

Design

Observational molecular characterization study

Authors

EDEmad DiabAin Shams UniversityABAbdel-Hamid I. BazidUniversity of Sadat CityMFMohamed FawzySuez Canal University

Discussion

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Implication

Serotype O predominance may guide Egyptian FMD vaccine selection; leaves open need for ongoing regional surveillance.

Study Design

Type

Observational (n=51)

PICO

P
Population
51 oral tissue samples from cattle and buffaloes with suspected foot-and-mouth disease across six Egyptian governorates during 2013-2014 outbreaks.
E
Exposure / Comparator
Foot-and-mouth disease virus (FMDV) infection
O
Primary Outcome
Detection and serotyping of FMDV by RT-PCR

Limitations

  • Small sample size of 51 samples
  • Need for further studies to determine the immunogenic relationship between vaccine strains and new strains

Cite This Study

Diab et al. (2019) conducted an observational in Foot-and-mouth disease (n=51). Foot-and-mouth disease virus (FMDV) infection was evaluated on Detection and serotyping of FMDV by RT-PCR. During the 2013-2014 foot-and-mouth disease outbreaks in Egypt, serotype O was the predominant circulating strain (70.45%), followed by serotype A (20.45%) and SAT2 (9.10%).

synapsesocial.com/papers/6a7066548031ec7bb1dc5007https://doi.org/10.14202/vetworld.2019.190-197
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular and serological typing of foot-and-mouth disease virus serotypes currently circulating in Egypt2021 · 15 citations
  2. 2Genetic Characterization of Foot and Mouth Disease Virus (FMD) Serotypes in Egypt (2016-2017) and Identification of a New Lineage of Serotype O Topotype EA-32019 · 11 citations
  3. 3Epidemiological and Genetic Insights of the Circulating Foot-and-Mouth Disease Virus Serotypes in Egypt2024 · 8 citations
  4. 4Molecular Epidemiology of FMDV in Northern Egypt (2012-214)2014 · 14 citations
  5. 5Mutations in foot and mouth disease virus types A and O isolated from vaccinated animals2020 · 8 citations