Key result
Regular sport physical activity is linked to ~32% lower CVD risk, predominantly in sedentary workers.
Why the study?
The independent and interacting long-term associations of occupational and sport physical activity with coronary heart disease and cardiovascular diseases in employed men were unclear.
Do sport physical activity and occupational physical activity have differing associations with cardiovascular risk in employed men?
Population
3574 employed men aged 25-64 years free of CVD at baseline in North Italy
Comparison
Different levels of occupational physical activity and sport physical activity
Design
Population-based and factory-based cohort study
Follow-up
Median 14 years
Authors
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Low/high OPA linked to higher CHD risk vs intermediate, SpPA benefit limited to low-OPA workers; supports OPA paradox but leaves causal inference open.
Cohort (n=3,574)
Yes
Do sport physical activity and occupational physical activity have differing associations with cardiovascular risk in employed men?
Hazard Ratio: 0.68 (95% CI 0.46–0.98)
p-value: p=0.04
Sport physical activity reduces cardiovascular risk primarily in sedentary workers, while high occupational physical activity may paradoxically increase risk.
Ferrario et al. (2018) conducted a cohort in Cardiovascular risk (n=3,574). Sport physical activity (SpPA) vs. Poor sport physical activity was evaluated on Incidence of cardiovascular diseases (CVD) (HR 0.68, 95% CI 0.46-0.98, p=0.04). Intermediate or recommended levels of sport physical activity reduced the risk of cardiovascular disease by 32% (HR 0.68) compared to poor sport physical activity, though this protective effect was prominent only in sedentary workers.
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