Key result
Ultra-low 20 mL contrast CTA provides interpretable TAVI planning images despite lower contrast-to-noise than controls.
Why the study?
An important group of TAVI candidates have severe renal failure, necessitating testing of a novel CTA protocol with ultralow contrast volume for imaging assessment.
Does an ultralow contrast volume (20 mL) CTA protocol provide adequate image quality for TAVI planning compared to standard protocols?
Observational (n=16)
Does an ultralow contrast volume (20 mL) CTA protocol provide adequate image quality for TAVI planning compared to standard protocols?
An ultralow contrast volume (20 mL) CTA protocol provides interpretable image quality for TAVI planning, which may be particularly beneficial for candidates with severe renal failure.
May support ultralow-contrast CTA in severe renal failure TAVI candidates; leaves open larger prospective validation before clinical adoption.
Transcatheter aortic valve implantation workup includes assessment of the aorta and the iliofemoral arteries by computed tomographic angiography. An important group of transcatheter aortic valve implantation candidates have severe renal failure. We tested a novel computed tomographic angiography protocol (128-detector-row dual-source scanner, high-pitch helical mode) with ultralow contrast volume (20 mL) in 8 patients, compared with 8 controls. Contrast-to-noise ratio and subjective image quality, albeit lower than in the controls, were suitable for interpretation in the ultralow contrast volume group throughout all measured locations.
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Azzalini et al. (2013) conducted an observational in Transcatheter aortic valve implantation (TAVI) planning (n=16). Ultra-low contrast computed tomographic angiography (CTA) protocol vs. Controls was evaluated on Contrast-to-noise ratio and subjective image quality. An ultra-low contrast CTA protocol (20 mL) for TAVI planning yielded contrast-to-noise ratios and image quality suitable for interpretation, despite being lower than controls.
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