Key result
Sokolow-Lyon ECG criteria best detect LVH in hypertensive Gambians, while Wolff performs best in non-hypertensives.
Why the study?
Existing ECG criteria for diagnosing LVH have been extensively studied in Caucasians but are inapplicable to people of African descent, necessitating evaluation against echocardiography in Gambians.
Which ECG criteria have the best accuracy for diagnosing left ventricular hypertrophy compared to echocardiography in adult Gambians?
Comparison
ECG criteria (Minnesota, Araoye, Sokolow and Lyon, Wolff) vs 2-D guided M-mode echocardiography using Penn formula
Design
Cross-sectional study
Authors
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May guide ECG selection for LVH in Gambians by hypertension status; leaves open prospective validation before practice change.
Cross-Sectional (n=316)
Single-blind
Yes
Which ECG criteria have the best accuracy for diagnosing left ventricular hypertrophy compared to echocardiography in adult Gambians?
In an adult Gambian population, the Sokolow-Lyon ECG criterion is the most accurate for diagnosing LVH in hypertensive patients, while the Wolff criterion is most accurate for non-hypertensive individuals.
Nkum et al. (2009) conducted a cross-sectional in Systemic hypertension (n=316). Electrocardiographic criteria (Sokolow-Lyon, Minnesota, Araoye, Wolff) vs. 2-D guided M-mode echocardiography (Penn formula) was evaluated on Distance from the top left-hand corner of the ROC curve for the Sokolow and Lyon criterion in hypertensives (cm). The Sokolow and Lyon ECG criterion demonstrated the best overall accuracy for diagnosing left ventricular hypertrophy in hypertensive adult Gambians (ROC distance 6.6 cm), whereas the Wolff criterion was most accurate in non-hypertensives.
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