What question did this study set out to answer?

To assess the efficacy and safety of combining endoscopic band ligation with submucosal sclerotherapy for treating gastric varices in patients with liver cirrhosis.

November 1, 2003Endoscopy

Clinical Evaluation of Combined Endoscopic Variceal Ligation and Sclerotherapy of Gastric Varices in Liver Cirrhosis

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To assess the efficacy and safety of combining endoscopic band ligation with submucosal sclerotherapy for treating gastric varices in patients with liver cirrhosis.
Interventional cohort of 56 patients with liver cirrhosis and gastric varices treated between June 1997 and May 2002 at a single center.
Intervention consisted of tightly ligating each gastric varix with O-rings followed by submucosal injection of 1% polidocanol around the ligated site, with supplementary sessions as needed.
Variceal bleeding achieved an initial hemostasis rate of 100%, with complete disappearance of gastric varices confirmed endoscopically in 100% of cases and no critical procedural complications.
During endoscopic follow-up, varices recurred in 7 of 56 patients (12.5%) and minor oozing occurred in 2 patients (3.6%); all were successfully retreated with no variceal bleeding deaths.

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Implication

Cohort study demonstrates 100% hemostasis following combined ligation and sclerotherapy in patients with liver cirrhosis, indicating a safe and accessible approach for gastric varices.

Cite This Study

Arakaki et al. (2003) studied this question.

synapsesocial.com/papers/6ab23db424acf28815d6369d https://doi.org/10.1055/s-2003-43475

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Implication

Cohort study demonstrates 100% hemostasis following combined ligation and sclerotherapy in patients with liver cirrhosis, indicating a safe and accessible approach for gastric varices.

Clinical Evaluation of Combined Endoscopic Variceal Ligation and Sclerotherapy of Gastric Varices in Liver Cirrhosis

Key Points

Discussion

Implication

Cite This Study

Clinical Evaluation of Combined Endoscopic Variceal Ligation and Sclerotherapy of Gastric Varices in Liver Cirrhosis

Key Points

Discussion

Implication

Cite This Study

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