Key result
Lifetime physical activity patterns are linked to altered risk for coronary heart disease.
Why the study?
Consequences of changing lifetime physical activity patterns on cardiovascular disease morbidity have rarely been described.
Do lifetime physical activity patterns reduce the risk of coronary heart disease in adults?
Case-Control (n=791)
Do lifetime physical activity patterns reduce the risk of coronary heart disease in adults?
This case-control study aims to evaluate the association between lifetime physical activity patterns and the risk of developing stable coronary heart disease.
No quantitative results reported; leaves open the association between lifetime activity patterns and CHD risk in case-control data.
The beneficial effect of physical activity on cardiovascular morbidity and mortality and on all cause mortality is widely acknowledged.1 However, most of the studies mainly or exclusively relied on reported current activity patterns and investigated mortality measures. In particular, consequences of changing physical activity patterns on cardiovascular disease morbidity have rarely been described.2 We therefore thoroughly reanalysed a case–control study of patients with stable coronary heart disease (CHD) to describe lifetime physical activity patterns and to estimate the risk for CHD associated with lifetime physical activity patterns after careful adjustment for other established risk factors. A detailed description of the study design and methods has been reported in a previous paper on the effects of current physical activity levels on CHD risk and the inflammatory response profile.3 Briefly, 312 patients aged 40–68 years with stable, angiographically confirmed CHD were enrolled. The control group consisted of 479 volunteers who were occasional blood donors and were frequency matched with the patient group for age and sex. The participation rate was 78% of eligible patients and 84% of eligible controls. The study was approved by the ethics committee of the University of Ulm. Each participant was interviewed about physical activity patterns during each of the following age spans: 20–39 years, …
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Dietrich Rothenbacher (2006) conducted a case-control in Stable coronary heart disease (CHD) (n=791). Lifetime physical activity patterns was evaluated on Risk for CHD. The truncated abstract describes a case-control study of lifetime physical activity patterns and coronary heart disease risk, but does not report quantitative results.
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