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Fukiic acid derivatives have been synthesized from 3,4-dimethoxyphenylpyruvic acid by a stereospecific method. The synthetic methyl (+)-erythro-2,3-dihydroxy-4-(3,4-climethoxyphenyl)-3-methoxycarbonylbutyrate was shown to be identical with natural O,O′-dimethylfukiic acid dimethyl ester by a direct comparison.
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Matsumoto et al. (1972) studied this question.
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