A Catalytic Multicomponent Approach for the Stereoselective Synthesis of cis‐4,5‐Disubstituted Pyrrolidinones and Tetrahydro‐3H‐pyrrolo[3,2‐c]quinolines

This is the authors' abstract. We don't add key points for this paper.

Ménage à trois: In a three-component reaction, furancarbaldehydes 1, anilines 2, and the monocyclopropanated pyrrole 3 can be assembled highly stereoselectively to give cis-4,5-disubstituted pyrrolidinones (see scheme; Boc=tert-butoxycarbonyl). The products are lead structures for pharmaceutically important compounds.