Key result
Decreasing post-pacemaker AV block is linked to significantly worse long-term survival.
Why the study?
The long-term natural history and significance of continuing changes in atrioventricular conduction after permanent pacemaker implantation in trifascicular disease were not well characterized.
Does the pattern of atrioventricular conduction change after permanent pacemaker implantation predict long-term survival in patients with trifascicular disease?
Comparison
Groups with no change, increasing, or decreasing atrioventricular block
Design
Cohort study
Follow-up
Average 40 months
Authors
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May signal higher mortality risk after PPM; hypothesis-generating and requires prospective validation before guiding care.
Cohort (n=72)
Does the pattern of atrioventricular conduction change after permanent pacemaker implantation predict long-term survival in patients with trifascicular disease?
p-value: p=<0.03
In patients with trifascicular disease and permanent pacemakers, decreasing A-V block over time is associated with worse long-term survival, potentially due to a higher prevalence of underlying coronary heart disease.
Lichstein et al. (1976) conducted a cohort in Trifascicular disease (n=72). Decreasing A-V block vs. Increasing A-V block or no change in A-V conduction was evaluated on Long-term survival (p=<0.03). Decreasing A-V block after permanent pacemaker implantation was associated with a significantly decreased probability of long-term survival compared to increasing or no change in conduction (P<0.03).
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