Key result
Prolonged physical immobilization alongside antipsychotics is linked to fatal pulmonary thromboembolism in psychiatric inpatients.
Why the study?
Pulmonary thromboembolism may be a cause of sudden death in hospitalized psychiatric patients, with unclear links to prolonged physical immobilization and associated risk factors.
Does prolonged physical immobilization increase the risk of fatal pulmonary thromboembolism in hospitalized psychiatric patients receiving antipsychotics?
Comparison
Prolonged physical immobilization with antipsychotic and diazepam therapy
Design
Retrospective observational analysis of medical records and autopsy findings
Follow-up
Mean hospital stay 8.2 days
Authors
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Prolonged immobilization may raise fatal PTE risk in psychiatric inpatients; hypothesis-generating and requires prospective confirmation before practice change.
Observational (n=5)
No
Does prolonged physical immobilization increase the risk of fatal pulmonary thromboembolism in hospitalized psychiatric patients receiving antipsychotics?
Prolonged physical immobilization combined with antipsychotic therapy may be a significant risk factor for fatal pulmonary thromboembolism in hospitalized psychiatric patients.
Stefanović et al. (2013) conducted an observational in Hospitalized psychiatric patients (n=5). Prolonged physical immobilization was evaluated on Fatal pulmonary thromboembolism. Prolonged physical immobilization (average 4.2 days) and antipsychotic therapy were present in all 5 cases of fatal pulmonary thromboembolism among hospitalized psychiatric patients.
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