Storage lesionChanges that alter the physiological properties occur in collected blood over time, and this is known as storage lesion.• Coagulation factor activity (including factor VIII) deteriorates very rapidly in whole blood, particularly after the first 24 hours of storage and is not a suitable product to treat haemostatic disorders.• Platelets in whole blood lose viability and functionality very quickly and are not a suitable source for treatment of patients requiring platelet therapy.
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Joel Hardwick (2008) studied this question.