Key result
Low birth weight was significantly associated with Legg-Perthes disease, with male infants weighing under 5.5 pounds being five times as likely to develop the disease as those weighing ≥8.5 pounds.
Why the study?
Is low birth weight associated with an increased risk of Legg-Perthes disease in children?
Case-Control (n=484)
Is low birth weight associated with an increased risk of Legg-Perthes disease in children?
Effect estimate: 5 times as liable
Low birth weight is significantly associated with an increased risk of developing Legg-Perthes disease, particularly in male infants.
No takes yet. Share an insight, caveat, or question.
No association with parental or perinatal factors; leaves open other etiologies for Legg-Perthes disease.
MOLLOY et al. (1967) conducted a case-control in Legg-Perthes disease (n=484). Low birth weight vs. Normal or high birth weight was evaluated on Legg-Perthes disease (5 times as liable). Low birth weight was significantly associated with Legg-Perthes disease, with male infants weighing under 5.5 pounds being five times as likely to develop the disease as those weighing ≥8.5 pounds.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: