Key result
BIS monitoring objectively measures hypnotic depth to detect intraoperative awareness, which affects up to ~0.4% of surgeries.
Why the study?
Intra-operative awareness under general anesthesia is rare but causes severe complications, and prevention is difficult due to challenges in measuring depth of hypnosis.
Does the bispectral index (BIS) system help prevent intra-operative awareness in patients undergoing general anesthesia?
Does the bispectral index (BIS) system help prevent intra-operative awareness in patients undergoing general anesthesia?
Intra-operative awareness is a rare but severe complication of general anesthesia, and the bispectral index (BIS) system may be a useful monitoring tool in high-risk patients.
Summary : The incidence and causes of awareness under general anesthesia are reviewed, as well as principles of prevention and management. Although intra-operative awareness is rare, occurring in 0.2-0.4% of all operations done under general anesthesia, it causes severe peri-operative and post-operative complications. Moreover, the incidence of awareness is higher in certain patients (e.g. those who are drug-tolerant), and certain procedures (e.g. cardiac surgery). Preventing awareness has been difficult because depth of hypnosis is difficult to measure. However, the bispectral index (BIS) system offers a new way to objectively measure depth of hypnosis. In most cases, BIS is not necessary, but in patients and procedures where the risk of awareness is high, BIS is a useful clinical tool. Methods : A Medline search was performed, crossing the medical subject headings "Awareness" and "General Anesthesia", and limiting the results to reviews or meta-analyses in English. This search yielded five relevant papers. The reference sections of these papers were searched to obtain other relevant papers.
No takes yet. Share an insight, caveat, or question.
Chen et al. (2003) conducted a review in Awareness under general anesthesia. Bispectral index (BIS) system was evaluated on Incidence of awareness under general anesthesia. Awareness under general anesthesia occurs in 0.2-0.4% of operations, and the bispectral index (BIS) system provides a useful clinical tool to objectively measure depth of hypnosis in high-risk cases.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: