The influence of Hofmeister's effect on the osmotic behavior of erythrocytes and on the state of water in their suspension

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The bulk phase of water and its status in the cells play an important role in the management of metabolic processes. One of the little‐known universal phenomenon associated with the state of water is the Hofmeister effect which influences interfacial surfaces, the conformation of macromolecules, enzyme activity, and the growth of microorganisms. We investigated the influence of this effect on the change in the cell's ability to adapt to changing osmotic conditions, since understanding the mechanisms of osmotic behavior of the cells is an important step in the management of their activity (start of endo‐ and exocytosis, apoptosis). It is shown that specific properties of anions in the medium correlate with the osmotic sensitivity of red blood cells (RBC) and with indicators of free and bound water in suspension. The lyotropic series anion solution effect on the cell is a change of the hydration and structure of the membrane, which determines the osmotic behavior of the cell and the water environment properties.