Key result
In-hospital clinical recovery is linked to a ~74% increase in rest-activity rhythm amplitude.
Why the study?
Hospitalization for acute illness is a major risk factor for rest-activity rhythm disturbance among elderly subjects, influenced by acute illness, aging, and hospital environment.
Observational (n=10)
Absolute Event Rate: 0.54% vs 0.31%
p-value: p=< 0.05
Rest-activity rhythms in elderly patients are severely altered upon acute care admission but progressively resynchronize with clinical improvement.
May prompt rhythm monitoring in hospitalized elderly; leaves open whether interventions mitigate disturbance.
Hospitalization for acute illness is a major risk factor of rest-activity rhythm disturbance among elderly subjects. The rest-activity rhythm is disturbed by the acute illness, aging and hospital environment. The purpose of this study is to assess the rest-activity rhythm and light exposure (using a wrist worn actigraph) of 10 patients (mean age 81 years, seven females) admitted on an acute care unit, suffering from cardiac, respiratory or renal acute disease. A non-parametric method was used to analyze activity data. With an improvement of the underlying diseases, the mean relative amplitude of rhythm increased from 0.31 +/- 0.19 for the first 5-day period after admission to 0.54 +/- 0.21 for the second period before discharge (P < 0.05). The amount of time at night spent above a lighting threshold of 50 lux decreased from 31.4 to 12.3 min between the two periods. The rhythm of elderly subjects hospitalized in the acute care unit is severely altered during the initial period and is progressively resynchronized following clinical improvement. Under the acute underlying disease and/or aging, environmental conditions (light, noise) should be considered to maintain regular rest-activity rhythm.
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Vinzio et al. (2003) conducted an observational in Cardiac, respiratory or renal acute disease (n=10). Clinical improvement during hospitalization vs. Initial 5-day period after admission was evaluated on Mean relative amplitude of rest-activity rhythm (p=< 0.05). Clinical improvement during hospitalization in an acute care unit was associated with an increase in the mean relative amplitude of rest-activity rhythm from 0.31 to 0.54 (P<0.05).
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