Key result
Two cases of pregnancy after living related liver transplantation resulted in 0 obstetric complications, full-term deliveries, and no deterioration of graft function during a 6-month follow-up.
Why the study?
Is pregnancy safe and successful in women who have undergone living related liver transplantation?
Case Report (n=2)
Is pregnancy safe and successful in women who have undergone living related liver transplantation?
Pregnancy can have favorable perinatal outcomes without deterioration of graft function in women after living related liver transplantation.
Answers are grounded in this paper and cite their sources.
May inform counseling on pregnancy after living related liver transplantation; hypothesis-generating and requires confirmation in larger cohorts.
BACKGROUND: Living related liver transplantation (LRLT) is currently the only available alternative to orthotopic liver transplantation that is of use in children with acute liver failure. There are reports of long-term survival in liver graft recipients who had been transplanted in childhood. In female patients of reproductive age it may also mean ability to conceive. CASE REPORT: We report 2 cases of successful pregnancies in women after living related liver transplantation. During the 6-month follow-up, no obstetric complications during pregnancy, delivery and postpartum period, and no deterioration of graft function were noted. The neonates were delivered full-term in good general condition, with no signs of intrauterine hypotrophy, congenital malformations or infection, and their psycho-motor development is perfectly normal. CONCLUSIONS: These 2 cases of pregnancies with favorable perinatal outcomes in women after living related liver transplantation, who delivered in our Department with no deterioration of graft function, may be regarded as evidence of full recovery in women after the LRTL procedure.
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Mirosław Wielgoś (2012) conducted a case report in Pregnancy after living related liver transplantation (n=2). Living related liver transplantation was evaluated on Obstetric complications, delivery outcomes, and graft function. Two cases of pregnancy after living related liver transplantation resulted in 0 obstetric complications, full-term deliveries, and no deterioration of graft function during a 6-month follow-up.
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