Key result
Radiofrequency ablation abolishes antegrade accessory pathway conduction earlier than retrograde conduction in WPW.
Why the study?
It is unclear whether abolition of antegrade and retrograde accessory pathway conduction during ablation therapy occurs simultaneously.
Does radiofrequency ablation abolish antegrade and retrograde accessory pathway conduction simultaneously in Wolff Parkinson White syndrome?
Case Report (n=1)
Does radiofrequency ablation abolish antegrade and retrograde accessory pathway conduction simultaneously in Wolff Parkinson White syndrome?
This case demonstrates that during radiofrequency ablation of an accessory pathway, antegrade conduction can be abolished before retrograde conduction.
A 36 year-old man with Wolff Parkinson White syndrome due to a left-sided accessory pathway (AP) was referred for catheter ablation. Whether abolition of antegrade and retrograde AP conduction during ablation therapy occurs simultaneously, is unclear. At the ablation procedure, radiofrequency delivery resulted in loss of preexcitation followed by a short run of orthodromic tachycardia with eccentric atrial activation, demonstrating persistence of retrograde conduction over the AP after abolition of its antegrade conduction. During continued radiofrequency delivery at the same position, the fifth non-preexcitated beat failed to conduct retrogradely and the tachycardia ended. In this case, antegrade AP conduction was abolished earlier than retrograde conduction.
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Hadid et al. (2012) conducted a case report in Wolff Parkinson White syndrome (n=1). Radiofrequency catheter ablation was evaluated on Abolition of antegrade and retrograde accessory pathway conduction. During radiofrequency catheter ablation for Wolff Parkinson White syndrome, antegrade accessory pathway conduction was abolished earlier than retrograde conduction.
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