Key result
A 78-year-old male patient illustrates the diagnostic pitfall of myxofibrosarcoma, an aggressive soft tissue neoplasm requiring complementary stainings for accurate diagnosis.
Case Report (n=1)
Highlights the diagnostic challenges of myxofibrosarcoma and the necessity of complementary stainings to avoid misdiagnosis.
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May prompt complementary stainings in suspected myxofibrosarcoma; leaves open validation of diagnostic algorithms in larger cohorts.
Myxofibrosarcoma (MFS) is a variant of the group of malignant fibrous histiocytomas. It is one of the most aggressive types of soft tissue neoplasms. The clinical presentation is not pathognomonic and the histological aspects are highly heterogenous, frequently delaying the diagnosis or leading to misdiagnosis. Complementary histochemical and immunohistochemical stainings are mandatory to achieve the diagnosis of MFS. A 78-year-old male patient is presented illustrating this diagnostic pitfall. Extensive surgery followed by radiotherapy is the first choice treatment.
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Castronovo et al. (2013) conducted a case report in Myxofibrosarcoma (n=1). Extensive surgery followed by radiotherapy was evaluated. A 78-year-old male patient illustrates the diagnostic pitfall of myxofibrosarcoma, an aggressive soft tissue neoplasm requiring complementary stainings for accurate diagnosis.
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